KPV(LYSINE-PROLINE-VALINE)

KPV is a simple, naturally occurring tripeptide (three amino acids long) derived from the C-terminal end of the anti-inflammatory hormone $alpha$-Melanocyte-Stimulating Hormone ($alpha$-MSH). It is a potent anti-inflammatory agent that works intracellularly by blocking the activation of $text{NF}-kappa text{B}$ (a master regulator of inflammation) and promoting the integrity of tissue barriers, especially in the gut. It is widely researched for conditions involving chronic inflammation, such as Inflammatory Bowel Disease (IBD), colitis, and skin conditions like eczema.