Description
ACE-031 is a recombinant fusion protein — an engineered construct combining the extracellular domain of the activin receptor IIB with an antibody Fc fragment — designed to bind and neutralise myostatin and related TGF-β superfamily ligands. That receptor-decoy mechanism is what separates ACE-031 from the myostatin-binding approach used by Follistatin elsewhere in this catalogue, since ACE-031 works by mimicking the receptor rather than sequestering the ligand through a natural binding protein.
Researchers studying myostatin-pathway inhibition frequently compare ACE-031 against Follistatin to characterise how different neutralisation strategies (receptor-decoy versus natural binding protein) affect downstream muscle-signalling research outcomes.
For laboratory research use only. Reconstitute with bacteriostatic water and store refrigerated, protected from light.
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